Director of ELIXIR Open Data in action: How ELIXIR meets the challenge of sustainable life science data The challenges in storing, integrating and analysing the data from modern biological experiments needs a coordinated effort that involves both national and international resources. ELIXIR, the European life-science infrastructure for biological information, is a European research infrastructure that bring together national life-science data centres, services, and core bioinformatics resources from the 20 member states into a single, coordinated infrastructure. Open access to bioinformatics resources provides a valuable path to discovery. ELIXIR is identifying core data resources that are essential to the larger international community and is developing a robust framework to secure their long-term sustainability and accessibility. Some of these datasets are highly specialised and by coordinating local, national and international resources – hosted at over 120 institutes - the ELIXIR infrastructure will meet the data-related needs of Europe’s 500,000 life-scientists. ELIXIR is currently constructing a distributed e‐infrastructure of bioinformatics services – a data nodes network - built around established European centres of excellence. This talk will discuss our approaches to handling, accessing and archiving large and also highly diverse data‐sets in the human translational medicine space and how ELIXIR, in partnership with national cohorts and efforts such as the Global Alliance for Genomics and Health. The talk will discuss experiences in data integration and the need for establishing data‐management plans within projects that address the issues of meta‐data annotation and long term archiving. Bio Niklas Blomberg is the Director of ELIXIR, the European infrastructure for bioinformatics and life-science data, based in Hinxton, UK. He currently coordinates EXCELERATE - and EU H2020 project with 45 partners and 29 M€ funding to develop the ELIXIR infrastructure and CORBEL (35 partners, 14M€) to drive interoperability between European life science research infrastructure. Niklas holds a BSc in Chemistry from Göteborg University and a PhD from the European Molecular Biology Laboratory (EMBL), Heidelberg where he worked on structural bioinformatics and protein NMR spectroscopy in the group of Michael Nilges. In 1999 he joined AstraZeneca's Structural Chemistry Lab in Mölndal, Sweden as a computational chemist and has during his 12 year tenure with AZ worked on topics such as fragment-based lead generation and compound screening collection enhancements. As Associate Director of Computational Chemistry he led the global cheminformatics group, located in UK and Sweden for 6 years. In 2011-2013, he built a new, cross-disciplinary team for Computational Chemistry and Computational Biology to support Respiratory, Inflammation and Autoimmune research from target nomination to clinical candidate nomination. He is an industry advisor in national eScience initiatives, until recently chair of BILS, the Swedish ELIXIR node, and has co-chaired the IMI Open PHACTS initiative.