Ibrahim Emam is a Research Associate at the Data Science Institute at Imperial College leading the development of IMI eTRIKS Harmonization Service Platform (eHS). Before that he was working as a senior software engineer at the Functional Genomics group at the European Bioinformatics Institute developing the Gene Expression Atlas and ArrayExpress2. He received his MSc in Bioinformatics from the University of Oxford and his dual BSc in Computer Science and Biology from the American University in Cairo in Egypt. His working experience revolves around bioinformatics application design and development, large scale data management and analysis, data standardization, modeling and visualisation.
Title: eTRIKS Data Harmonization Service Platform: putting standards into action
A common feature of translational research studies is their approach to generate diverse types of biological and medical data bridging the otherwise disjoint domains of clinical and basic research. To realize the main benefits of a translational approach in observing and integrating clinical and biomedical data it is pivotal to develop a unified metadata infrastructure to serve a common repository for standards compliant translational data. Thus preserving the data for reuse, validation and enabling cross-study data exploration and analysis. Biospeak-DB is a new standards compliant repository part of the eTRIKS Harmonization Service platform (eHS) for storing, sharing and querying harmonized translational research data based on a generic metadata model. The metadata model we develop builds on already existing standard initiatives in clinical and molecular (omics) data management, namely the CDISC standard for clinical data as well as study design elements and the ISA standard for ‘omics studies (samples & assays).