Bio Kees van Bochove is founder and CEO of The Hyve, a company dedicated to the support and facilitation of open source, open standards and open data in bioinformatics and translational research. He studied Computer Science at University of Utrecht and Bioinformatics at VU University Amsterdam,for which he did his research project on lipoprotein metabolism at TNO Quality of Life in Zeist and the Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University Boston. Kees is also an advisor in the Dutch startup scene, as StartupDelta advisor for Neelie Kroes, in the Advisory Boards of UtrechtInc and DTL, and is engaged with patient advocacy organisations such as the Movember Foundation. He has been lead architect in several international open source projects. Currently, he is active in the tranSMART initiative, as member of the Board of Directors of tranSMART Foundation and leading the Foundations’ Architecture Working Group. Title: Key learnings from The Hyve in TraIT and IMI: Combining TranSMART with Pre-clinical, Wearable and Real world data Abstract The Hyve is an active member of the CTMM (Center for Translational Molecular Medicine) Translational Research IT (TraIT) project, a part of a €300M Dutch public-private consortium which aims to develop a long-lasting IT infrastructure for the Netherlands that will facilitate the collection, storage, analysis, archiving and securing of the data generated in the CTMM’s twenty-one disease area focused operational research projects. TranSMART is used in CTMM TraIT as one of the main tools for the integration, normalization, and alignment of data. It permits users from the CTMM disease projects to explore and share data very efficiently to formulate new research strategies. The Hyve is also providing tranSMART services, such as scientific data curation and loading, as well as infrastructure support and software development, in a number of other public-private consortia, such as IMI eTRIKS, IMI EMIF, IMI Translocation and IMI RADAR-CNS. In this talk, Kees van Bochove, founder and CEO of The Hyve, will reflect on the use of tranSMART as a key data integration tool for translational research, and highlight a number of ongoing developments in tranSMART, such as the system’s integration and data curation support tooling in CTMM TraIT, the wearables data support that is being developed in RADAR-CNS and new user interfaces development in IMI Translocation.